Effect of Yogurts Supplemented With Mobilee on Joint Function in Healthy Individuals With Joint Discomfort

Bioiberica

Status: Completed

Conditions: Low Intensity Knee Gonalgia

Treatments: Dietary Supplement: Yogurt supplemented with Mobilee; Dietary Supplement: Yogurt

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT01303432

CTNS 001_03_2010

Details and patient eligibility

About

The purpose of this study is to determine whether the daily eating of a yogurt supplemented with Mobile is effective in improving joint function and quality of life of individuals with low intensity gonalgia.

Full description

The prevalence of low intensity gonalgia is relatively high in western population. The purpose of the present intervention study is to determine whether the daily consumption of a yogurt supplemented with Mobile is effective in improving joint function and quality of life of individuals with low intensity gonalgia. Previous research using in vitro and animal models have demonstrated the efficacy of Mobilee in reducing inflammation and promoting anabolic responses in joint tissues. In addition, in two previous human intervention trials, the effects of Mobilee in joint function had been assessed using isokinetic tests. The present trial aims to confirm those previous results.

Enrollment: 80 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adult (between 20 and 70 years of age)
• Subject with low intensity knee gonalgia (VAS pain intensity between 3 and 5cm during at least the last 6 months)
• Healthy individual according to its medical records, physical and laboratorial parameters
• Positive informed consent

Exclusion criteria

• Individuals requiring acetaminophen or any other drug to control pain
• Active rheumatoid arthritis or any other inflammatory joint disease
• Oral treatment with corticosteroids 4 weeks before selection
• Intra-articular treatment with corticosteroids 3 months before selection
• Significant injury of the study joint 12 months before selection
• Individuals receiving any drug or supplement for osteoarthritis
• Individuals requiring any type of medical prescription to control pain

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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80 participants in 2 patient groups, including a placebo group

Mobilee yogurt

Experimental group

Description:

Subjects eating daily on yogurt supplemented with Mobilee

Treatment:

Dietary Supplement: Yogurt supplemented with Mobilee

Placebo yogurt

Placebo Comparator group

Description:

Subjects receiving daily a standard yogurt

Treatment:

Dietary Supplement: Yogurt