Effect of Zinc Suplementation on Serum Hemosystein Level in Hemodialysis Patients

Shiraz University of Medical Sciences

Status: Completed

Conditions: End Stage Renal Failure

Treatments: Drug: Zinc Supplement; Drug: placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT01101217

4542

Details and patient eligibility

About

The purpose of this study is to study the effect of zinc supplementation in end stage renal failure on hemocystein level.

Full description

hemocystein increased in end stage renal failure and zinc involved in hemocystein metabolism thus zinc supplementation may be effective on hemocystein level.

Enrollment: 100 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• hemodialysis for 3 months
• older than 18 years old
• serum level of zinc less than 72.6 microgram/ l in men and less than 70 microgram/ l in female

Exclusion criteria

• acute renal failre
• malabsorption
• history of steroid or cytotoxic consumption

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

100 participants in 2 patient groups, including a placebo group

placebo

Placebo Comparator group

Description:

placebo for 6 weeks

Treatment:

Drug: placebo

zinc

Active Comparator group

Description:

zinc sulfate 220 mg per day orally for 6 weeks

Treatment:

Drug: Zinc Supplement