Effect on Postoperative Sore Throat of Lidocaine Jelly Application Over the Endotracheal Tube of Tapered-shaped Cuff

Keimyung University

Status and phase: Unknown; Phase 4

Conditions: Sore Throat

Treatments: Drug: Normal saline application; Drug: Lidocaine jelly application

Study type: Interventional

Funder types: Other

Identifiers

NCT02952157

LidoTaper

Details and patient eligibility

About

Postoperative sore throat is a complication after general anesthesia requiring endotracheal intubation. The investigators will evaluate the efficacy of lidocaine jelly application on the endotracheal tube with taper-shaped cuff regarding postoperative sore throat.

Enrollment: 210 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I-III
• Patients scheduled for general anesthesia with endotracheal intubation
• Patients scheduled for surgery which duration is expected to less than 3 hr

Exclusion criteria

• Difficult airway
• Rapid sequence induction
• Recent sore throat
• Recent upper respiratory infection
• Asthma
• Chronic obstructive pulmonary disease
• Chronic cough
• Pregnancy
• Allergy to lidocaine
• Friable teeth
• History of head and neck surgery
• Multiple intubation attempts
• Regional anesthetic agents
• Gastric tube
• Dexamethasone

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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210 participants in 2 patient groups

Control

Sham Comparator group

Description:

Normal saline will be applied to the endotracheal tube.

Treatment:

Drug: Normal saline application

Lidocaine

Active Comparator group

Description:

Lidocaine jelly will be applied to the endotracheal tube.

Treatment:

Drug: Lidocaine jelly application