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Effectiveness and Safety of Limbal Relaxing Incisions for Correcting Post Phacoemulsification High Astigmatism

A

Assiut University

Status and phase

Not yet enrolling
Phase 1

Conditions

Phacoemulsification
Astigmatism

Treatments

Procedure: Limbal relaxing incisions

Study type

Interventional

Funder types

Other

Identifiers

NCT06896357
LRIs in high astigmatism

Details and patient eligibility

About

To compare the effect of Limbal relaxing incisions (LRIs) plus spectacle correction versus spectacle correction alone on subjective and objective improvement in visual function for correcting post phacoemulsification high astigmatism .

Full description

Astigmatism is one of the commonest refractive errors encountered during our clinical practice. Surgically induced astigmatism is the main obstacle to achieve good uncorrected visual acuity following cataract surgery. It is estimated that corneal astigmatism of more than 1.0 diopter (D) is found in up to 40% of patients presenting for cataract surgery, 1.5D or more is present in over 20% and above 2.0D in 10%.

Astigmatism induces distortion of the image leading to compromise quality of vision. In order to achieve better visual results, the effect of postoperative astigmatism should be minimized, management options for corneal astigmatism include glasses, contact lenses, and surgery such as Limbal relaxing incisions (LRIs), refractive laser surgery, toric lenses or rarely corneal grafting. The LRIs technique involves the placement of incisions corresponding to the steep meridian, resulting in corneal flattening and the reduction of astigmatic power. LRI is a safe and an inexpensive procedure, which is simple for experts to perform. Although most of the nomograms recommended that LRIs technique can correct up to 3 D of astigmatism ,it has been found that it is possible to correct even more than 4 D if the incisions were performed on high degrees of astigmatism.

Enrollment

30 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Conventional phacoemulsification was done at least one month earlier.
  • Clear cornea with corneal astigmatism more than 3.0 D.

Exclusion criteria

  • History of corneal surgeries (e.g., keratoplasty, refractive surgery, and corneal wound repair).
  • Ocular trauma.
  • Other intraocular surgery.
  • Patient with corneal opacities.
  • Thin cornea .
  • Any significant ocular disease causing diminution of vision (e.g., optic atrophy, diabetic retinopathy, and age-related macular degeneration), autoimmune disease, and peripheral corneal disease.

Trial design

Primary purpose

Treatment

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

30 participants in 1 patient group

patients with post phacoemulsification high astigmatism .
Experimental group
Treatment:
Procedure: Limbal relaxing incisions

Trial contacts and locations

0

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Central trial contact

youstina shaheir gad, resident doctor

Data sourced from clinicaltrials.gov

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