Effectiveness if Premedication With Single Dose Piroxicam and Prednisolone After a Single Visit Root Canal Treatment .

Dow University of Health Sciences

Status and phase: Completed; Phase 3; Phase 2

Conditions: Post-operative Endodontic Pain

Treatments: Drug: Piroxicam 20 mg; Drug: prednisolone 20 mg

Study type: Interventional

Funder types: Other

Identifiers

NCT04124822

Dikiohs2013

Details and patient eligibility

About

Two drugs (Piroxicam and Prednisolone)are being compared for post operative endodontic pain after a single visit root canal treatment for 74 hours.

Full description

To evaluate effectiveness of single dose premedication with piroxicam(20mg) and prednisolone(20mg) on post endodontic pain after a single visit root canal treatment .

patient will be recalled every day for 4 days to know the pain scale using visual analogue scale .

Enrollment: 60 patients

Sex: All

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patient ages from 20-40 years(28).
2. Single rooted tooth with symptomatic irreversible pulpitis.
3. With no analgesic or anti-inflammatory drug taken within a week period before procedure.

Exclusion criteria

1. Patients presenting with any systemic disease
2. Patients already taking premedication for endodontic pain.
3. Pregnant or lactating patients.
4. Multirooted teeth.
5. Teeth with Pulpal necrosis.
6. Previously treated or initiated root canal treatment.
7. Patient presenting with allergy due to drug

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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60 participants in 3 patient groups

control

No Intervention group

Description:

group 1 , is no intervention group in which root canal procedure will be done without drug as ideal protocol .

Piroxicam

Experimental group

Description:

group 2 is given Piroxicam 20 mg half an hour before root canal treatment to manage post operative pain.

Treatment:

Drug: Piroxicam 20 mg

Prednisolone

Experimental group

Description:

group 3 is given Prednisolone 20mg half an hour before root canal treatment to manage post operative pain.

Treatment:

Drug: prednisolone 20 mg