Effectiveness of a Person-centred Prescription Model at the End of Life

Matia Foundation

Status: Completed

Conditions: Geriatrics; End-Of-Life; Inappropriate Prescribing; Palliative Medicine; Deprescriptions

Treatments: Other: Person-Centred Prescription Model

Study type: Interventional

Funder types: Other

Identifiers

NCT05454644

PCP-EOL

Details and patient eligibility

About

This study's main objective is to investigate whether the application of an adapted person-centred prescription model during a hospital stay would reduce the use of inappropriate or futile regular medications in older people at the end of life, improving their clinical/health statuses and reducing the expense associated with pharmacological treatment. We hypothesised that applying this modified method could optimise pharmacotherapeutic indicators and the expense associated with the pharmacological treatment of hospitalised patients

Enrollment: 114 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients admitted to the geriatric convalescence unit and identified as having a non-oncological advanced chronic disease and being in need of palliative care, with a limited survival prognosis according to the necessity of palliative care (NECPAL) test.

Exclusion criteria

• Patients with hospital stays of less than 72 hours.
• Patients transferred to other hospitals or units.
• Patients with imminently terminal patients.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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114 participants in 2 patient groups

Usual Pharmaceutical Care

No Intervention group

Description:

Patients in the control arm receive usual pharmaceutical care in hospital. Reconciliation of the medication at hospital admission and a validation of the treatment modifications during the hospitalisation is carried out.

Person-Centred Prescription Model

Experimental group

Description:

An interdisciplinary medicine-optimisation strategy is implemented in people at the end of life (EOL) based on the person-centred prescription (PCP).

Treatment:

Other: Person-Centred Prescription Model