Effectiveness of a VAP Prevention Bundle in the PICU

Institute of Hospitalization and Scientific Care (IRCCS)

Status: Unknown

Conditions: Ventilator Associated Pneumonia

Treatments: Other: Measures for the VAP prevention in the PICU; Other: Evaluation of VAP incidence before the protocol introduction

Study type: Observational

Funder types: Other

Identifiers

NCT03763695

1855

Details and patient eligibility

About

This observational monocentric prospective study aims to evaluate the efficacy of new measures for ventilator associated pneumonia (VAP) management in the pediatric population in the pediatric intensive care unit (PICU) of Fondazione Policlinico Agostino Gemelli of 8 beds. The investigators will compare the incidence of VAP in the group of patients in which this protocol has been implemented to a retrospective control group of patients before the new protocol implementation. VAP bundle includes oral care hygiene measures (i.e chlorhexidine swab), to keep clean and dry ventilator circuits and head positioning at 45 degrees.

Enrollment: 242 estimated patients

Sex: All

Ages: Under 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age < 18 years
• patients receiving mechanical ventilation for more than 48 hours

Exclusion criteria

• no informed consent
• pregnancy
• previous endotracheal antibiotic therapy

Trial design

242 participants in 2 patient groups

Retrospective control group

Description:

Patients admitted in our PICU before the implementation of the protocol for VAP prevention (from 01/01/2016 to 12/31/2017)

Treatment:

Other: Evaluation of VAP incidence before the protocol introduction

Prospective group

Description:

Patients admitted to our PICU since the VAP bundle has been introduced in the clinical practice (from 01/01/2018)

Treatment:

Other: Measures for the VAP prevention in the PICU