Effectiveness of an Adapted Physical Activity Program on Improving the Health-related Quality of Life of Women With Endometriosis in Martinique (APAENDO)

University Hospital Center of Martinique

Status: Completed

Conditions: Endometriosis

Treatments: Other: Adapted physical activity (APA)

Study type: Interventional

Funder types: Other

Identifiers

NCT06776627

2024-A01875-42 (Other Identifier)

24_RIPH2-03

Details and patient eligibility

About

There is no specific treatment for endometriosis, because the pathophysiology is poorly understood.

Adapted physical activity (APA) is recognized as a beneficial supportive care for patients suffering from chronic pathology. Adapted physical activity can play a role in managing endometriosis symptoms. Studies have shown that regular physical exercise can help reduce pain, improve quality of life and alleviate symptoms related to chronic diseases.

However, it is known that few women with endometriosis have regular physical activity because of pain, chronic fatigue that lead to activity limitation or even disability.

This study provides an opportunity to evaluate the impact of regular APA practice on improving the quality of life and symptoms of women with endometriosis in Martinique.

Based on this, APA could be included in the endometriosis care pathway in Martinique.

Full description

The investigators' hypothesis is that APA improves the overall quality of life of women with endometriosis and also has a positive impact on pain, functional abilities and sleep. The effectiveness of the proposed adapted physical activity program also improves the psycho-social and professional impact of the disease in the daily lives of patients.

Enrollment: 51 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult woman of childbearing age,
• Clinico-radiological or clinico-histological diagnosis of endometriosis: laparoscopy with biopsy or MRI,
• History of endometriosis symptoms before diagnosis,
• Walking without technical assistance,
• Able to read and write,
• Patient wishing to improve her health by optimizing her lifestyle,
• Patient affiliated or beneficiary of a social security scheme,
• Patient having given free, informed and written consent.

Exclusion criteria

• Acute or terminal illness,
• Recent fracture of the upper or lower limbs (< 3 months),
• Other chronic unstable or orthopedic illness that could interfere with the ability to participate in a physical activity program,
• Resting ECG at inclusion outside the normal range,
• Patients who practice moderate to intense physical activity for more than 150 minutes per week,
• Absolute contraindication to physical activity linked to severe co-morbidities,
• Patient placed under legal protection, guardianship or curatorship,
• Pregnant or breastfeeding woman.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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51 participants in 2 patient groups

Routine care

No Intervention group

Description:

31 patients: Routine consultation including: * clinical examination * pain scale * ECG * vital signs * fat and muscle mass * medical history * biological assessment * quality of life questionnaire (EHP-30) * sedentary lifestyle and physical activity test * sleep scale (PSQI)

Routine care + adapted physical activity (APA)

Experimental group

Description:

Patients randomized to the APA group will be prescribed, at the end of the routine consultation, 12 weeks of adapted physical activity sessions, to be carried out outdoors, and coordinated by a qualified professional from the STAPS sector (Master's degree in Science and Technology of Physical and Sporting Activities). The latter will provide patients with an adapted program determined following a personalized physical condition assessment: aerobic capacity, strength, endurance, flexibility, balance and proprioception tests.

Treatment:

Other: Adapted physical activity (APA)