Effectiveness of Atypical Versus Conventional Antipsychotics in Treating Schizophrenia

Yale University

Status and phase

Completed

Phase 4

Conditions

Schizophrenia

Treatments

Drug: quetiapine

Drug: risperidone

Drug: olanzapine

Study type

Interventional

Funder types

Other

NIH

Identifiers

NCT00237861

MH57292

R01MH057292 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study will compare the effectiveness of newer atypical antipsychotics versus older conventional antipsychotics in treating schizophrenia.

Full description

At seven participating hospitals, acutely exacerbated patients with schizophrenia were randomly assigned to treatment with antipsychotic from the atypical class vs antipsychotic from the conventional class. Medication choice within class, dose, concomitant medications, and other prescribing decisions were left to the community prescriber. Patients were followed for one year after discharge.

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria