Effectiveness of Auto-adjusted Continuous Positive Airway Pressure for Long-term Treatment of Sleep Apnea

Konrad E. Bloch

Status

Completed

Conditions

Sleep Apnea, Obstructive

Treatments

Device: automatic CPAP devices

Device: constant CPAP devices

Study type

Interventional

Funder types

Other

Identifiers

NCT00280800

EK 1187

Details and patient eligibility

About

Hypothesis: Computer controlled continuous positive airway pressure (autoCPAP) is equally effective in improving obstructive sleep apnea syndrome symptoms, breathing disturbances, objective vigilance, and it is cost-effective compared to conventional fixed continuous positive airway pressure.

Full description

To investigate whether computer controlled continuous positive airway pressure (autoCPAP) improves subjective sleepiness, quality of life, objective vigilance, and nocturnal respiration to a similar degree as conventional fixed continuous positive airway pressure in the initial phase of treatment and over the subsequent 2 years during home therapy
To investigate the cost of autoCPAP compared to fixed CPAP therapy

Enrollment

208 patients

Sex

All

Ages

18 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Excessive sleepiness, and Epworth Sleepiness Score > or = 8
Apnea- Hypopnea-Index (AHI) > or = 10/hour
Age 18-75

Exclusion criteria

Psychophysiological incapacity to perform questionnaires
Other sleep disorders
Psychiatric disease requiring treatment
Previous CPAP therapy
Previous uvulopalatopharyngoplasty
Chronic nasal obstruction that required treatment for more than 1 month
Cancer
COPD, with FEV1 < 50% predicted
Symptomatic cardiovascular disease requiring treatment defined as congestive heart failure > NYHA II
Previous stroke with neurological residuum
Cheyne-Stokes respiration
Chronic pain syndromes, fibromyalgia
Drug or alcohol addiction