Effectiveness of Bisacodyl Suppository Agent for Dose Reduction of Low Dose PEG

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Samsung Medical Center

Status

Completed

Conditions

Bowel Preparation

Treatments

Drug: 1L PEG-Asc
Drug: Bisacodyl 10Mg Suppository
Drug: 2L PEG-Asc

Study type

Interventional

Funder types

Other

Identifiers

NCT03849196
2017-05-100

Details and patient eligibility

About

Proper bowel cleansing before colonoscopy is an important factor to increase the detection rate of lesions. Low volume polyethylene glycol (PEG) plus ascorbic (PEG-Asc) has reduced the dosage of previous bowel preparation agent, but it still presents discomfort to patients. The aim of this study was to confirm the efficacy and convenience of volume reduction of PEG-Asc by adding bisacodyl suppository at the same day by compared with conventional 2L PEG-Asc.

Full description

Eligibility criteria: outpatients between the ages of 20 and 70 years, who were scheduled for colonoscopy between August 2017 and January 2018 Exclusion criteria: patients with a history of gastrointestinal tract surgery, inflammatory bowel disease, severe active colitis, underlying chronic kidney disease, or pregnancy. Outcome measures: the Boston Bowel Preparation Scale (BBPS)

Enrollment

168 patients

Sex

All

Ages

20 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

outpatients who were scheduled for colonoscopy between August 2017 and January 2018

Exclusion criteria

  • History of gastrointestinal tract surgery
  • History of inflammatory bowel disease
  • History of severe active colitis
  • History of chronic kidney disease
  • pregnant woman.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

168 participants in 2 patient groups

2L PEG-Asc
Experimental group
Description:
2L PEG-Asc for bowel preparation
Treatment:
Drug: 2L PEG-Asc
1L PEG-Asc & 'Bisacodyl 10Mg Suppository
Active Comparator group
Description:
1L PEG-Asc with 'Bisacodyl 10Mg Suppository for bowel preparation
Treatment:
Drug: Bisacodyl 10Mg Suppository
Drug: 1L PEG-Asc

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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