Effectiveness of Cannabidiol Vs. Narcotics for Post Operative Pain Control in Elective Shoulder Arthroscopic Surgery (CBDS)

Foundation for Orthopaedic Research and Education

Status and phase: Completed; Early Phase 1

Conditions: Post-operative Pain

Treatments: Drug: Cannabidiol Oil

Study type: Interventional

Funder types: Other

Identifiers

NCT05240755

USF003668

Details and patient eligibility

About

This study is a prospective, randomized, nonblinded trial to evaluate the effectiveness of Cannabidiol (CBD) oil on post-operative pain control compared to opioid medications.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18 years or older
• Requiring shoulder arthroscopic surgery for soft tissue pathology
• Able to complete surveys and follow-up visits

Exclusion criteria

• Younger than 18 years of age
• Shoulder dislocation, fracture, previous surgery, coexisting extremity pathology, pregnancy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 3 patient groups

Standard of Care

No Intervention group

Description:

Opioid standard of care: Tramadol 50 mg PO PRN #30, Hydrocodone/Acetaminophen 5/325 PO PRN #30

Cannabidiol Oil 100 mg

Experimental group

Description:

CBD 100 mg PO liquid suspension QD starting 30 days prior and finishing 30 days post-op

Treatment:

Drug: Cannabidiol Oil

Cannabidiol Oil 200 mg

Experimental group

Description:

CBD 200 mg PO liquid suspension QD starting 30 days prior and finishing 30 days post-op

Treatment:

Drug: Cannabidiol Oil