Effectiveness of Combining Erector Spinea Block With Non Opioid Infusions as Opioid Free Anesthesia in Spine Surgeries.

Ain Shams University

Status: Not yet enrolling

Conditions: Spine Fusion; Opioid Use

Treatments: Drug: fentanyl infusion after general anesthesia and erector spinea block; Drug: lidocaine 2% and dextometometidine infusion after general anesthesia and erector spinea block

Study type: Interventional

Funder types: Other

Identifiers

NCT05850468

MS81/2023

Details and patient eligibility

About

opioid free anesthesia consists of combination of pharmacological and non pharmacological modalities that target different pathways of pain mechanism. combining myofascial plane blocks with infusion of adjuvants such as lidocaine or dexmedetomidine can offer equivalent intraoperative hemodynamic stability compared to that of opioid with better pain control postoperatively. this study will investigate the efficacy of combined erector spina block with lidocaine and dexmedetomidine infusion as opioid sparing anesthesia in spine surgeries

Full description

patients who will undergo spine surgery will be allocated into two groups. after general anesthesia, bilateral erector spine block will be applied in both groups. group A will have intraoperative fentanyl infusion and group B will have lidocaine and dexmedetomidine infusion in 50 ml syringe till end of surgery

Enrollment: 140 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• spine surgery ASAI,II

Exclusion criteria

• revision surgery hypotension bradycardia

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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140 participants in 2 patient groups

traditinal balanced anesthesia

Active Comparator group

Description:

fentanyl infusion after general anesthesia and erector spinea block

Treatment:

Drug: fentanyl infusion after general anesthesia and erector spinea block

opioid free anesthesia

Experimental group

Description:

lidocaine and dextometidine infusion after general anesthesia and erector spinea block

Treatment:

Drug: lidocaine 2% and dextometometidine infusion after general anesthesia and erector spinea block