Effectiveness of Creatine on Pain, Fatigue, and Muscle Architectural Variables in Patients Witg Fibromyalgia. (SECPFMAPFM)

Camilo Jose Cela University

Status: Invitation-only

Conditions: Fibromyalgia

Treatments: Dietary Supplement: Creatine; Dietary Supplement: Dextrose

Study type: Interventional

Funder types: Other

Identifiers

NCT06675708

FIBYSAR2

Details and patient eligibility

About

Creatine, a non-protein organic amino acid, is synthesized from arginine, glycine, and methionine. The use of creatine has been shown to be effective in healthy subjects, providing benefits primarily in terms of strength, which has been the main factor studied. In patients with various conditions, including pain, creatine supplementation has demonstrated a reduction in pain and even cognitive improvements.

Due to creatine's general improvement in muscular endurance and fatigue.

Full description

Through this study, we aim to analyze whether creatine supplementation can be beneficial in reducing symptoms in patients with Fibromyalgia. Previous studies have demonstrated its benefits, and therefore, we want to evaluate if these benefits can manifest in a shorter time compared to previous studies in patients with Fibromyalgia.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with FM
• aged between 18 and 75 years
• agree to participate and sign the informed consent

Exclusion criteria

• who do not have recent surgeries
• patients with reduced mobility
• adequate level of comprehension to be able to answer the questionnaires that will be provided in the study
• If they are taking antihypertensive medications

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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80 participants in 2 patient groups, including a placebo group

Experimental group

Experimental group

Description:

The creatine experimental group will receive 20g of creatine for 5 days, divided into 4 equal doses, followed by 5g/day as a single dose for the duration of the trial.

Treatment:

Dietary Supplement: Creatine

Placebo group

Placebo Comparator group

Description:

The placebo group will receive 20g of dextrose for 5 days, divided into 4 equal doses, followed by 5g/day as a single dose for the duration of the trial

Treatment:

Dietary Supplement: Dextrose