Effectiveness of Detachment of the Breathing Circuit on the Rate of DLT Malposition After Postural Change

Shandong First Medical University

Status: Not yet enrolling

Conditions: Intratracheal Intubation; Patient Positioning

Treatments: Behavioral: Disengage the breathing circuit

Study type: Interventional

Funder types: Other

Identifiers

NCT06182371

MLv

Details and patient eligibility

About

The goal of this clinical trial is to assess the incidence of double-lumen endobronchial tube displacement in patients undergoing thoracic surgery with a change in position, compared with double-lumen endobronchial tube malposition in chest surgery patients with a fixed breathing circuit. The study is to investigate: whether detaching the breathing circuit in patients undergoing thoracic surgery would reduce the rate of double-lumen endobronchial tube malposition, the incidence of postoperative pulmonary complications, and improve patient outcomes.

Participants will be randomly divided into a disconnected breathing circuit group and a breathing circuit connected group and after entering the operating room, the intravenous access will be opened, and blood pressure, heart rate, electrocardiogram, oxygen saturation, arterial pressure, and end-expiratory carbon dioxide will be monitored. Anesthesia induction will be performed by an anesthesiologist, and then the double-lumen endobronchial tube will be inserted under laryngoscopic guidance. Will the catheter be delivered to the expected depth, the double-lumen endobronchial tube will be connected to the anesthesia machine for mechanical ventilation.

Researchers will compare the malposition rate of the double-lumen endobronchial tube when the patient transitions from the supine to lateral decubitus position, the effect of single-lung ventilation, oxygen saturation at 5 and 10 minutes after single-lung ventilation, and postoperative recovery time.

Enrollment: 256 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA I-II elective surgery for patients
• Patients undergoing thoracic surgery requiring a left-sided double-lumen endobronchial tube;
• Sign the informed consent form for this clinical study.

Exclusion criteria

• Mouth opening <3cm;
• History of previous difficult intubation;
• Patients with diseases of the upper respiratory tract and main bronchi;
• Cardiac insufficiency;
• People with liver dysfunction;
• Renal insufficiency;
• Previous stroke;
• Patients with severe obstructive ventilation dysfunction;
• Bronchial asthma or airway hyperresponsiveness;
• Patients who have participated in other clinical studies in the past 3 months.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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256 participants in 2 patient groups

Disengagement of the breathing circuit

Experimental group

Description:

When the patient's position is changed from the supine position to the lateral decubitus position, the anesthesiologist disengages the breathing circuit.

Treatment:

Behavioral: Disengage the breathing circuit

Connect the breathing circuit

No Intervention group

Description:

When the patient's position is changed from the supine position to the lateral decubitus position, the anesthesiologist maintains the normal connection of the breathing line.