Effectiveness of Family-based Intervention for Youn Persons With Eating Disorders (VIBUS-wp1)

Mental Health Services in the Capital Region, Denmark

Status: Enrolling

Conditions: Eating Disorders

Treatments: Behavioral: Family-based treatment

Study type: Observational

Funder types: Other

Identifiers

NCT05956366

H-17022391

Details and patient eligibility

About

This research project aims to characterize a naturalistic cohort of children and adolescents with eating disorders in terms of biological, psychological and psychopathological features. Further, the project will examine the effectiveness of treatment, the determinants of treatment outcome and the course of treatment response for children and adolescents with eating disorders (ED), treated in a generic specialist child and adolescent mental health service. The first choice of treatment is outpatient family-based treatment (FBT), which has documented effect for anorexia nervosa and bulimia nervosa. However, a subgroup of young persons with eating disorders does not respond sufficiently to this treatment, and evidence concerning effective treatment for children and adolescents with atypical eating disorders is still lacking. Further, treatment effectiveness for children and adolescents in a Danish naturalistic setting has never been examined.

Full description

The overall aim is to assess associations between patient characteristics and treatment response across the spectrum of eating disorders to identify, which patients benefit from family based treatment, and which patients possibly would need other kinds of treatment or more intensive care.

Research questions:

1. Which patient and family characteristics predict faster recovery from ED in childhood and adolescence?

2. Which patient and family characteristics predict intensification of treatment in the forms of day hospital or full hospitalization?

3. At which time point can recovery be predicted based on information from initial assessment and/or assessment during the course of treatment?

4. Which patient and family characteristics (e.g. patterns of comorbid symptoms) are common in those not responding well to treatment within each diagnostic category?

5. How many young patients migrate between ED diagnoses, and what characterizes these patients?

6. Studies on treatment effectiveness for EDNOS in children and adolescents are still lacking. Hence, an important research question of this study is whether family based treatment for EDNOS is effective and is perceived as helpful by patients and families?

   In addition, the project will seek to answer the following:

7. Is treatment effectiveness in The Capital Region of Denmark (BUC) comparable to published results from other countries in the same age group?

Enrollment: 1,000 estimated patients

Sex: All

Ages: 7 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• begin treatment for eating disorder

Exclusion criteria

• lack of informed consent

Trial design

1,000 participants in 3 patient groups

Anorexia nervosa

Description:

Children and adolescents presenting for treatment for anorexia nervosa typica or atypica (ICD-10: F50.0 or F50.1)

Treatment:

Behavioral: Family-based treatment

Bulimia nervosa

Description:

Children and adolescents presenting for treatment for bulimia nervosa typica or atypica (ICD-10: F50.2 or F50.3)

Treatment:

Behavioral: Family-based treatment

Other eating disorders

Description:

Children and adolescents presenting for treatment for other eating disorders (ICD-10: F50.8)

Treatment:

Behavioral: Family-based treatment