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Effectiveness of Immersive Virtual Reality Combined With Occupational Therapy in Reducing Fall Risk and Frailty Among Older Adults (VIRTO-FRAIL)

U

Universidad Rey Juan Carlos

Status

Not yet enrolling

Conditions

Fall Prevention in Healthy Aging
Frailty Syndrome
Older Adults, Balance

Treatments

Procedure: Conventional occupational therapy sessions
Procedure: Inmersive Virtual Reality

Study type

Interventional

Funder types

Other

Identifiers

NCT07060677
080520254252025

Details and patient eligibility

About

Population aging is a growing global phenomenon that poses significant challenges to healthcare systems, particularly in preventing falls and managing frailty among older adults. Falls remain a leading cause of morbidity and mortality in this population, affecting approximately one-third of individuals over 65 each year. At the same time, frailty syndrome (FS)-a clinical condition marked by progressive decline in physical and cognitive function-significantly increases the risk of falls, disability, and dependency. Pre-frailty, an intermediate and reversible stage, offers a key opportunity for preventive interventions.

Scientific evidence supports the effectiveness of interdisciplinary approaches to address frailty and fall prevention. In this context, occupational therapy plays a central role by promoting functional autonomy through meaningful activities. However, traditional approaches may be limited in individuals with low motivation or mild cognitive impairment. Therefore, integrating innovative technologies such as immersive virtual reality (IVR) emerges as a promising therapeutic strategy.

IVR enables users to interact with simulated three-dimensional environments, enhancing cognitive stimulation, motor training, and treatment adherence. Modern devices like the Meta Quest 3 headsets provide accessible, safe, and adaptable immersive experiences, with reported benefits in balance, gait, attention, and motivation. Nonetheless, no studies to date have specifically evaluated the effectiveness of this technology when combined with conventional occupational therapy to reduce fall risk and frailty in older adults.

This project proposes a pilot randomized controlled trial (RCT), lasting 5 months, using a single-blind, parallel-group design. It will be conducted at the Bouco Madrid Ferraz Residential Center (Madrid, Spain), following CONSORT 2010 methodological guidelines. The primary aim is to assess the efficacy of a combined intervention using IVR through Meta Quest 3 headsets and occupational therapy, compared to conventional occupational therapy alone, in reducing fall risk, improving frailty status, enhancing quality of life, and increasing rehabilitation motivation in older adults.

The sample will include 30 participants (15 per group), selected based on specific inclusion and exclusion criteria. Participants will be randomly assigned to a control group (CG), receiving standard occupational therapy, or to an experimental group (EG), receiving a combined intervention of occupational therapy and IVR using the Kinesix XR platform, which is designed to enhance balance.

The intervention will last 8 weeks, with two one-hour sessions per week. The experimental group will receive 30 minutes of occupational therapy and 30 minutes of IVR per session. Assessments will be conducted at baseline, post-intervention, and at a 3-month follow-up using validated scales to measure fall risk, balance, frailty level, quality of life, and satisfaction.

Data will be pseudonymized, statistically analyzed using SPSS, and managed in compliance with the European General Data Protection Regulation (EU 2016/679). The small sample size reflects the exploratory nature of the study, aimed at assessing feasibility, safety, and preliminary outcomes prior to conducting a larger-scale trial.

Ultimately, this project aims to provide initial evidence on an innovative intervention for older adults by integrating digital tools with conventional therapeutic approaches. If proven effective, the VIRTO-FRAIL model could lay the groundwork for new strategies in geriatric rehabilitation and fall prevention.

Enrollment

30 estimated patients

Sex

All

Ages

65+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Individuals aged 65 years or older
  • Regularly attending rehabilitation treatment at the Bouco Madrid Ferraz Residence
  • Having the ability to walk with or without assistive devices
  • Presenting sufficient cognitive capacity to understand instructions (score ≥ 24 on the MMSE)
  • Agreeing to participate voluntarily
  • Signing the informed consent form.

Exclusion criteria

  • Having a diagnosis of a severe neurological disease (such as advanced Parkinson's disease or ALS, among others)
  • Having a history of epilepsy or seizures (due to potential adverse effects with VR)
  • Experiencing cardiovascular instability or having a medical contraindication for physical activity
  • Presenting vestibular disorders
  • Participating in other similar intervention programs during the same period
  • Being unable to use virtual reality glasses due to intolerance or dizziness
  • Not agreeing to participate voluntarily in the study and/or not signing the informed consent form.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

30 participants in 2 patient groups

Experimental Group (EG)
Experimental group
Description:
Experimental Group (EG), which received therapy with Inmersive Virtual Reality, plus their conventional occupational therapy sessions.
Treatment:
Procedure: Inmersive Virtual Reality
Procedure: Conventional occupational therapy sessions
Control Group (CG)
Active Comparator group
Description:
Control Group (CG), which received their usual sessions of conventional occupational therapy.
Treatment:
Procedure: Conventional occupational therapy sessions

Trial documents
1

Trial contacts and locations

2

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Central trial contact

Cristina García-Bravo

Data sourced from clinicaltrials.gov

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