Effectiveness of Interpersonal Psychotherapy (IPT) for Men and Women Prisoners With Major Depression

Brown University

Status and phase: Completed; Phase 3

Conditions: Major Depressive Disorder

Treatments: Behavioral: Group IPT for Depression + TAU

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT01685294

1R01MH095230-01

R01MH095230 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study will examine the effects of a first-line treatment for major depressive disorder (MDD), interpersonal psychotherapy (IPT), among men and women prisoners.

Full description

The purpose of this 3-year randomized trial is to promote uptake of evidence-based treatment in criminal justice settings by conducting a fully-powered randomized effectiveness study that collects pilot implementation data, including cost-effectiveness data. Group IPT will be compared to treatment as usual (TAU) in a sample of 90 male and 90 female prisoners with MDD from 4 institutions, allowing us to explore gender effects.

Enrollment: 181 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Meet all DSM-IV criteria for primary (non-substance induced) major depressive disorder
• Expectation of at least 6 months of incarceration at baseline interview
• Incarcerated for at least 4 weeks

Exclusion criteria

• Lifetime:

  • Bipolar disorder
  • Psychotic disorder

• Are imminently suicidal

• Cannot understand English well enough to understand the consent form or assessment instruments when read aloud

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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181 participants in 2 patient groups

Treatment as Usual (TAU)

No Intervention group

Description:

Standard prison mental health treatment instead of the research groups, including individual therapy, medication, etc.

Group Interpersonal Psychotherapy (IPT) for Depression + TAU

Experimental group

Description:

Participants will receive Group IPT for Depression + TAU.

Treatment:

Behavioral: Group IPT for Depression + TAU