Effectiveness of Intracytoplasmic Sperm Injection and Laser Assisted Hatching on in Vitro Fertilization Outcomes of Patients With Different Causes of Infertility

Far Eastern Memorial Hospital

Status: Completed

Conditions: Infertility

Study type: Observational

Funder types: Other

Identifiers

NCT02026661

102160-E

Details and patient eligibility

About

To determine the association of factors affecting the clinical pregnancy and live birth rates in patients undergoing in vitro fertilization (IVF) who received intracytoplasmic sperm injection (ICSI) and/or laser assisted hatching (LAH) or neither.

After applying the inclusion and exclusion criteria, a total of 400 women who underwent IVF between January 2007 and December 2010 were included in the analysis. Patients were divided into 4 groups; 1) those that did not receive ICSI or LAH, 2) those that received ICSI only, 3) those that received LAH only, and 4) those that received both ICSI and LAH. Univariate and multivariate analyses were performed.

Enrollment: 375 patients

Sex: Female

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• The present study was a retrospective review of the outcomes of women who underwent IVF with or without intracytoplasmic sperm injection (ICSI) at the Far Eastern Memorial Hospital, Taipei, Taiwan, between January 2007 and December 2010.

Exclusion criteria

• Cases in which estradiol levels exceeded 50 pg/mL on the second day of the menstrual cycle were excluded.
• Female minors or disabled persons.

Trial design

375 participants in 4 patient groups

those that did not receive ICSI or LAH

those that received ICSI only

those that received LAH only

those that received both ICSI and LAH