Effectiveness of Intravenous Tranexamic Acid in Reducing Blood Loss During and After Cesarean Section

Ain Shams Maternity Hospital

Status and phase: Unknown; Phase 4

Conditions: Bleeding

Treatments: Drug: Tranexamic Acid

Study type: Interventional

Funder types: Other

Identifiers

NCT02279186

septemper 2014

Details and patient eligibility

About

In this study, the efficacy and safety of tranexamic acid in the reducing the blood loss during and after elective LSCS will be investigated.

Full description

To state the effectiveness clinically and laboratory and safety of tranexamic acid in reducing blood loss during and after the elective lower segment cesarean section.

Enrollment: 200 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• • Women undergoing caesarean delivery for various elective indications.
• Full term primiparas / multiparas.
• Singleton pregnancy being delivered by LSCS.

Exclusion criteria

• • Medical problems involving the heart, liver, kidney and brain .
• Blood disorders.
• Allergy to tranexamic acid.
• History of thromboembolic disorders, abnormal placentation, severe pre-eclampsia, uterine anomalies and pathology.
• Multiple pregnancy, macrosomia.
• Polyhydromnios .
• Patients requiring blood transfusion due to anemia

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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200 participants in 2 patient groups

group A

Active Comparator group

Description:

receiving tranexamic acid

Treatment:

Drug: Tranexamic Acid

group B

No Intervention group

Description:

does not receive tranexamic acid