Effectiveness of Khat on Eyelid Wound Healing After Oculoplastic Surgery - a Prospective Study.

Sheba Medical Center

Status: Unknown

Conditions: Edema; Surgical Wound; Surgery; Eye Bruise; Hematoma

Treatments: Biological: Khat leaves

Study type: Interventional

Funder types: Other

Identifiers

NCT03917641

SHEBA-17-4804-GBS-CTIL

Details and patient eligibility

About

The post operative routine after Oculoplastic Surgery includes usage of cold compressions for symptomatic relief and decreasing of the edema and local hematomas in the first few days after the surgery. Khat (Catha edulis) is a plant that is used mainly for chewing and has a known stimulating effect, some patients report major improvement after including these leaves in the compressions they use after surgery. Khat contains the chemical ingredients Cathine and Cathinone, which are amphetamine-like alkaloids and probably the main contributors for its active effects. Our main goal is to use compressions that include the Khat leaves and check their effect on reducing the edema and hematomas after oculoplastic surgery.

Enrollment: 10 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients who underwent blepharoplasty and/or ptosis repair

Exclusion criteria

• Patients who were operated on one eye only
• Patients who underwent a different surgery in each eye

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Patients after Oculoplastic surgery

Experimental group

Description:

Each participant will use one compression with Khat leaves and another standard compression and will decide on which eye to use which compression. The compressions will be used for 10 minutes per every waking hour in the first 2 days post-op. The patient will take pictures of both his eyes in days 1,3 and 7 post operative days.

Treatment:

Biological: Khat leaves