Effectiveness of Large Language Model-Based Chatbot in Improving HPV Vaccine Awareness, Intention and Vaccination Rates

Xiamen University

Status: Not yet enrolling

Conditions: HPV Vaccination Rates; HPV Vaccination Intention; HPV Vaccine Awareness

Treatments: Device: Scientific videos; Device: Vaccine chatbot

Study type: Interventional

Funder types: Other

Identifiers

NCT07351604

HPV-AI-001

Details and patient eligibility

About

This is an interventional study targeting parents of junior high school girls and female university students. The primary objective of the study is to evaluate the effectiveness of a vaccine chatbot in improving HPV vaccination rates. The secondary objectives are to evaluate the effectiveness in improving vaccine awareness and vaccination intention. All participants will be enrolled and randomly assigned to four groups: (1) vaccine chatbot plus scientific videos, (2) vaccine chatbot only, (3) scientific videos only, and (4) a control group (no intervention). The chatbot will provide immediate, validated answers to participants' HPV vaccine-related questions. The scientific videos will cover content related to HPV vaccine safety, efficacy, and other relevant information. The study will compare changes in HPV vaccine awareness, vaccination intention, and vaccination behavior between the intervention groups and the control group after the intervention to evaluate whether the three intervention strategies enhance HPV vaccine awareness, vaccination intention, and vaccination uptake.

Enrollment: 36,000 estimated patients

Sex: All

Ages: 9+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Parents of junior high school girls / Female university students.
2. Possess an electronic device with QR code scanning capability.
3. The daughters / female university students have no contraindications to HPV vaccination.
4. No mental disorders or visual/reading impairments; able to cooperate with and implement the corresponding intervention activities.
5. Have provided informed consent and are willing to participate in the study.

Exclusion criteria

-

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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36,000 participants in 4 patient groups

Vaccine chatbot + Watching scientific videos group

Experimental group

Description:

The chatbot will provide immediate, validated answers to participants' HPV vaccine-related questions. Scientific videos cover content related to HPV vaccine safety, efficacy, and other relevant information.

Treatment:

Device: Vaccine chatbot

Device: Scientific videos

Watching scientific videos group

Experimental group

Description:

Scientific videos cover content related to HPV vaccine safety, efficacy, and other relevant information.

Treatment:

Device: Scientific videos

Vaccine chatbot group

Experimental group

Description:

The chatbot will provide immediate, validated answers to participants' HPV vaccine-related questions.

Treatment:

Device: Vaccine chatbot

Control group

No Intervention group

Description:

No intervention