Effectiveness of Lung Sono in One-lung Ventilation

Seoul National University

Status: Completed

Conditions: One Lung Ventilation

Treatments: Procedure: Lung-sono guided

Study type: Interventional

Funder types: Other

Identifiers

NCT03770793

JHSeo_LungSono

Details and patient eligibility

About

To observe the effectiveness of ultrasound-guided alveolar recruitment in thoracic surgery with one-lung ventilation(OLV).

Full description

One-lung ventilation(OLV) is essential in thoracic surgery for patient safety and better surgical view. However, pulmonary complications such as hypoxemia may be caused by OLV which might be preventable with adequate alveolar recruitment and positive end-expiratory pressure(PEEP). Alveolar recruitment has been performed with conventional methods without diagnostic tools in clinical setting.

Ultrasound is a non-invasive, radiation-free device with high accuracy for the diagnosis of lung atelectasis. There are a few reports regarding the usefulness of lung ultrasound in other surgeries, but not in thoracic surgeries with OLV.

Thus, investigators designed a study to observe the effectiveness of ultrasound-guided alveolar recruitment in thoracic surgery with OLV.

Enrollment: 166 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elective thoracic surgery which requires one-lung ventilation with lateral decubitus position

Exclusion criteria

• Patients who refuse to agree
• Previous lung surgical history
• History of pneumothorax or bullae
• Severe cardiopulmonary disease, COPD
• Operation time < 1hr

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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166 participants in 2 patient groups

Lung-sono guided

Experimental group

Description:

Before starting one-lung ventilation, alveolar recruitment is performed under the examination with ultrasound. Find the minimal airway pressure that actually starts to resolve the observed atelectasis. Repeat alveolar recruitment with the minimal pressure untill the atlelectasis is not visible.

Treatment:

Procedure: Lung-sono guided

Conventional

No Intervention group

Description:

Before starting one-lung ventilation, alveolar recruitment is performed with the pressure of 30mmHg for 10 seconds which is a conventional method.