Effectiveness of Nutritional Products to Treat Moderate Acute Malnutrition

Centre for Food and Nutrition Research, Yaounde

Status and phase: Completed; Phase 2

Conditions: Wasting; Moderate Acute Malnutrition

Treatments: Dietary Supplement: A daily ration of 40 kcal/kg of body weight during 56 days

Study type: Interventional

Funder types: Other

Identifiers

NCT01898871

CMR6010

Details and patient eligibility

About

The purpose of this study is to determine whether an improved corn-soya blend (CSB+) and a new formulated ready-to-use supplementary food (RUSF) are effective in the treatment of moderate acute malnutrition in children.

Full description

Assuming the availability of some food in the household, the caregivers were instructed on how best to use the food they have and the quantity of supplementary food distributed was calculated to provide about 50% of child energy requirement.

Enrollment: 81 patients

Sex: All

Ages: 6 to 59 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children aged 6-59 month
• Weight-for-height between -3 and -2 z-scores without edema
• Good appetite
• Stable clinical conditions

Exclusion criteria

• Weight-for-Height Z-score < -3
• Presence of bilateral pitting edema
• Unstable clinical conditions
• Not showing appetite

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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81 participants in 2 patient groups

Ready to Use Suplementary Food (RUSF)

Experimental group

Description:

A daily ration of 40 kcal/kg of body weight during 56 days

Treatment:

Dietary Supplement: A daily ration of 40 kcal/kg of body weight during 56 days

Corn Soya Blend (CSB+)

Active Comparator group

Description:

A daily ration of 40 kcal/kg of body weight during 56 days

Treatment:

Dietary Supplement: A daily ration of 40 kcal/kg of body weight during 56 days