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Effectiveness of Olive Oil Local Application in Orthodontic Patients.

M

Minia University

Status and phase

Unknown
Phase 1

Conditions

Orthodontic Tooth Movement

Treatments

Drug: Olive Oil Topical Oil

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

The large body of evidence supports the chemotherapeutic potential of substances found in Olive Oil (OO), acting on different sides, such as inflammation, oxidative damage, and even epigenetic modulation. The consumption of OO should be suggested in a healthy diet instead of other types of oils. It looks worthy, to determine the effect of local application of Olive Oil in decreasing the friction between brackets and wires during orthodontic treatment.

Full description

During the orthodontic treatment, the friction between the bracket and the arch-wire could prevent the action of forces required for a particular tooth movement. Studies demonstrated that approximately 12 to 60% of the force used to move a tooth is dissipated in the form of friction. Consequently, a delay could occur in the biological response to orthodontic movement. The most important factors that may have an impact on friction are; the composition of the bracket, the arch-wire alloy, the cross-sectional size of the arch-wire, the type of ligation system and the surface roughness of the bracket-archwire assembly.

In addition to the factors related to the orthodontic appliances, saliva is considered to be a biological variable associated with friction, as it acts as a lubricant during sliding mechanics.This fact should be taken into account in laboratory studies that aim to evaluate the performance of the archwire-bracket combinations. However, in the majority of the research studies, the friction test has been conducted without the use of any lubricant, which does not represent the clinical reality where there is saliva introduced during the movement of the arch-wire on the bracket. To remedy this situation, distilled water has been used as a lubricant. Although in this case the test is conducted in the presence of a lubricant, water does not have the lubricating ability of natural human saliva.

It is well known that oil is a well-known lubricant. But how we can use it to decrease friction between brackets and wires? and which type of oil we can use safely in patient mouth? Olive oil (OO) (Olea europaea, Oleaceae) is a fundamental component of the Mediterranean Diet; it is a mix of fatty acids such as oleic and linoleic acid, secoiridoids (oleuropein and oleocanthal), simple phenols (tyrosol and hydroxytyrosol), lignans (pinoresinol), flavonoids (apigenin), hydrocarbons (squalene), triterpenes (maslinic acid), and phytosterols (β-sitosterol).

The large body of evidence supports the chemotherapeutic potential of substances found in OO, acting on different sides, such as inflammation, oxidative damage, and even epigenetic modulation. The consumption of OO should be suggested in a healthy diet instead of other types of oils. It looks worthy, to determine the effect of local application of Olive Oil in decreasing the friction between brackets and wires during orthodontic treatment.

Enrollment

110 estimated patients

Sex

All

Ages

15 to 20 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  1. The age of patients ranges from 15-20 years old.
  2. Mild to moderate dental irregularity requiring non-extraction treatment.
  3. Presence of all the permanent teeth at least up to the first molars.
  4. Good oral hygiene, and periodontal health.

Exclusion criteria

  1. Patients require orthognathic surgery to correct skeletal discrepancies.
  2. patients who are taking medications, like NSAIDs or other anti-inflammatory drugs.
  3. cleft lip or palate patients.
  4. patients with hypodontia, or hyperdontia.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

110 participants in 2 patient groups

Placebo
No Intervention group
Description:
controlling group who will receive traditional orthodontic treatment.
Olive Oil
Experimental group
Description:
experimental group who will receive the local application of Olive Oil five times daily after teeth brushing
Treatment:
Drug: Olive Oil Topical Oil

Trial documents
1

Trial contacts and locations

1

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Central trial contact

Asmaa Mahmoud, lecturer; Ahmed Nasef, lecturer

Data sourced from clinicaltrials.gov

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