Effectiveness of Oral Anticoagulants in Elderly Patients With Non-Valvular Atrial Fibrillation and Heart Failure

Bristol-Myers Squibb (BMS)

Status: Completed

Conditions: Atrial Fibrillation; Heart Failure

Treatments: Other: Non-Interventional

Study type: Observational

Funder types: Industry

Identifiers

NCT03508271

CV185-681

Details and patient eligibility

About

Observational study of elderly individuals diagnosed with Non-Valvular Atrial Fibrillation and Heart Failure who are beginning oral blood thinners

Enrollment: 60,000 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Were age greater than or equal to 65 years as of the index date
• Had greater than or equal to 1 diagnosis of AF prior to or on the index date
• Had greater than or equal to 1 diagnosis claim of HF during the 12 months prior to or on the index date
• Had 1 or more pharmacy claim for oral blood thinners

Exclusion criteria

• Claims indicating diagnosis or procedure for hip/knee replacement surgery within 6 weeks prior to index date
• Pharmacy claim for warfarin, apixaban, dabigatran, edoxaban or rivaroxaban during the 12-month baseline period
• Greater than 1 oral anticoagulants prescription claim on the index date and/or with a follow-up less than 1 day
• Had medical claim indicating VTE in the 12 months prior to index date

Other protocol defined inclusion/exclusion criteria could apply

Trial design

60,000 participants in 1 patient group

Elderly individuals with NVAF and HF who are taking OAC's

Treatment:

Other: Non-Interventional