Effectiveness of Oral Iron Therapy in Iron Deficiency Anemia With Daily vs Alternate Day Dosing

University of Child Health Sciences and Children's Hospital, Lahore

Status and phase: Completed; Phase 3

Conditions: Iron Deficiency Anemia; Iron Deficiency Anemia Treatment

Treatments: Drug: Ferrous sulphate

Study type: Interventional

Funder types: Other

Identifiers

NCT07267975

No/1032/CH-UCHS

Details and patient eligibility

About

Treating iron deficiency anemia in children with daily and alternate day oral iron therapy

Full description

Comparison of effectiveness of oral iron in daily and alternate group in children

Enrollment: 60 patients

Sex: All

Ages: 1 day to 5 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

- Patients of both genders with ages in the range of 0 -60 months suffering from IDA as per operational definition.

Exclusion criteria

• Who have already taken treatment for IDA during last 2-months as per history/clinical record.

Who have undergone recent blood transfusion during last 12-weeks as per history/clinical record.

Children with chronic kidney disease, chronic liver disease, cardiac failure or concomitant malignancy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

60 participants in 2 patient groups

Continuous oral iron therapy

Active Comparator group

Description:

Oral iron daily dosing 6mg/kg/day

Treatment:

Drug: Ferrous sulphate

Drug: Ferrous sulphate

Intermittent oral iron

Experimental group

Description:

Oral iron therapy on alternate day with dose of 6mg /kg/day for 3 mons

Treatment:

Drug: Ferrous sulphate

Drug: Ferrous sulphate