Effectiveness of Port Site Bupivacaine Injection in Postoperative Pain Reduction After Lap. Chole

Hamdard University

Status and phase: Unknown; Phase 3

Conditions: Pain, Postoperative

Treatments: Drug: 0.25% Bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT05264805

N0333

Details and patient eligibility

About

To determine the effectiveness of port site bupivacaine infiltration in postoperative pain reduction after laparoscopic cholecystectomy.

Full description

The study is being done to determine the effectiveness of port site bupivacaine infiltration in postoperative pain reduction after laparoscopic cholecystectomy.

Enrollment: 166 estimated patients

Sex: All

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Patients of both the gender of age >18 years and <45years
2. Patients undergoing elective laparoscopic cholecystectomy under general anesthesia.
3. Patients with A.S.A grade I and II.

Exclusion criteria

1. Patients with known allergic reactions to local anesthetics.
2. Patients converted to open procedure.
3. Patients developing intra-operative complications.
4. Patients undergoing for laparoscopic cholecystectomy for acute cholecystitis.
5. Patients with obesity and chronic illness.
6. Patients with history of opioids, steroids, NSAIDs and alcohol use.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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166 participants in 2 patient groups

Bupivacaine group

Experimental group

Description:

Patient receiving 20ml of inj. 0.25% Bupivacaine at laparoscopic port site

Treatment:

Drug: 0.25% Bupivacaine

Placebo group

No Intervention group

Description:

No drug infiltration at laparoscopic port site