Effectiveness of Pumpkin Seed Extract on Improving Blood Sugar Level in Subhealth Subjects

Greenyn Biotechnology

Status: Enrolling

Conditions: Diabetes; Metabolic Disease

Treatments: Dietary Supplement: Pumpkin seed extract (High dose); Dietary Supplement: Pumpkin seed extract (Low dose); Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT05738655

A-111-110

Details and patient eligibility

About

This randomized, double-blind, placebo-controlled, and parallel clinical study aims to investigate the effectivness of a pumpkin seed extract on blood sugar management in subhealth people.

Enrollment: 60 estimated patients

Sex: All

Ages: 20 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Fasting blood sugar levels from 100 to 125 mg/dL
• Glycated hemoglobin levels from 5.7 to 6.4%
• 2-hour OGTT levels from 140 to 199 mg/dL

Exclusion criteria

• Pregnant women or preparing for pregnancy.
• Lactating women.
• Women gave birth 6 months before the study.
• Poor kindy funciton
• Severe cardiovascular or other chronic diseases
• Patients with type I or II diabetes
• Poor compliance
• Alcohol abuser
• Using anti-diabetic or weight managent supplements
• Blood transfusion three months before the study
• Pumpkin seed allergy

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 3 patient groups, including a placebo group

Placebo group

Placebo Comparator group

Description:

Placebo capsule, one capsule/day (300 mg/day) for 3 months

Treatment:

Dietary Supplement: Placebo

Low dose

Experimental group

Description:

Pumpkin seed extract capsule, one capsule/day (300 mg/day) for 3 months

Treatment:

Dietary Supplement: Pumpkin seed extract (Low dose)

High dose

Experimental group

Description:

Pumpkin seed extract capsule, two capsules/day (600 mg/day) for 3 months

Treatment:

Dietary Supplement: Pumpkin seed extract (High dose)