Effectiveness of Standard Therapy of Acne Vulgaris

University of Indonesia (UI)

Status: Completed

Conditions: Acne Vulgaris

Study type: Observational

Funder types: Other

Identifiers

NCT05982613

UIDV

Details and patient eligibility

About

This study was to evaluate the effectiveness of standard therapy for acne vulgaris (AV) based on the clinical practice guidelines (CPG) in Indonesia. The main questions it aims to answer were:

1. How is the clinical characteristics of patients with AV in dr.Cipto Mangunkusumo Hospital?
2. How is the effectiveness of standard therapy for AV based on the CPG in Indonesia in reducing the number of non-inflammatory, inflammatory, and total lesions and degree of acne severity?

The clinical pratice guideline (CPG) used for analysis was CPG by dr.Cipto Mangunkusumo Hospital 2017 in line with the date of patient visit. Data of 724 patients with AV in dr.Cipto Mangunkusumo Hospital as recorded in the medical records were assessed for eligibility. Data of 3-month-follow-up data of included subjects were collected and analyzed.

Full description

Objective: To evaluate the effectiveness of standard therapy for acne vulgaris (AV) based on the guidelines in Indonesia Design: An analytical retrospective observational study conducted from April 2023 through July 2023 using medical records of new acne patients between 2017 to 2019 from Dr. Cipto Mangunkusumo National Central General Hospital. A total sample of patients with AV who received standard therapy for acne vulgaris based on the guideline by Dr.Cipto Mangunkusumo Hospital in 2017 and not associated with systemic diseases or drugs were included. Patients were classified into mild, moderate, or severe acne using Lehmann grading system. Primary outcomes were changes in the number of non-inflammatory, inflammatory, and total lesions, and the proportion of acne severity after 3 months of therapy.

Enrollment: 724 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• New patients with acne vulgaris in the year 2017 to 2019
• Complete medical record data of 3-month follow-up, including data of: name, medical record number, sex, age, job, level of education, visit date, number of non-inflammatory, inflammatory, and total acne lesions, diagnosis of acne vulgaris based on Lehmann grading system
• Acne treatment based on clinical practice guideline by dr.Cipto Mangunkusumo Hospital 2017

Exclusion criteria

• Follow-up data less than 3 times in 3 months
• Incomplete medical record
• AV diagnosis without data on severity
• History of systemic diseases associated with acne such as polycystic ovarian syndrome and Cushing syndrome
• History of allergy with one or more standard acne therapy based on the clinical practice guideline
• Received acne therapy not aligned with clinical practice guideline by dr.Cipto Mangunkusumo Hospital

Trial design

724 participants in 1 patient group

General

Description:

This research is an observational study. There was no control and experimental group.