Effectiveness of the Cytokine Hemadsorption on Sepsis

Biruni University

Status: Completed

Conditions: Interleukin-6

Treatments: Procedure: cytokine hemadsorption

Study type: Observational

Funder types: Other

Identifiers

NCT05057455

BIRUNI 2

Details and patient eligibility

About

In this prospective study, we aimed to compare the laboratory and clinical results of cytokine hemadsorption as an immunomodulation therapy in ICU patients diagnosed with sepsis or septic shock.

Enrollment: 39 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• the patients were the available data of clinical and laboratory diagnosis of sepsis and septic shock
• detection of gram-negative bacterial agent in blood or sputum culture.
• patients who had the shock symptoms such as hypotension, tachycardia or fever during the course of sepsis.

Exclusion criteria

• had uncontrolled hemorrhage,
• diagnosed with cardiac failure at stage 4 or renal failure at stage 4 or hepatic liver failure at stage 4
• cancer at the end stage or admitted with acute coronary syndrome.

Trial design

39 participants in 1 patient group

ICU patients diagnosed with sepsis or septic shock

Description:

compare the laboratory and clinical results of cytokine hemadsorption as an immunomodulation therapy in ICU patients diagnosed with sepsis or septic shock.

Treatment:

Procedure: cytokine hemadsorption