Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences

Loma Linda University (LLU)

Status and phase: Begins enrollment in 2 months; Phase 3

Conditions: Dental Caries; Gingival Inflammation

Treatments: Drug: Conventional Toothpaste; Drug: Toothpaste Tablet

Study type: Interventional

Funder types: Other

Identifiers

NCT07124533

5250357

Details and patient eligibility

About

Objectives: To evaluate the effectiveness of toothpaste tablets when compared to conventional dentifrices in removing plaque.

Methods: 50 participants are randomized into two groups: Denttabs toothpaste tablets (T) and Colgate's Cavity Protection toothpaste (P). Both groups utilize their assigned dentifrice for 6 weeks. A pre and post-assessment measures the Gingival Index (GI) and Plaque Index (PI) and Decayed, Missing and Filled Teeth (DMFT). A questionnaire on the use of the product is distributed at the end of the study.

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Subjects are 18 years or older;
2. Subjects who will comply with study protocol;
3. Subjects who can read and understand the consent form;
4. Subjects available during the study period;
5. Subjects have more than 20 teeth.

Exclusion criteria

1. Subjects under the age of 18.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

Toothpaste Tablet

Experimental group

Description:

Subjects are instructed to use one toothpaste tablet at each brushing. Brushing is recommended twice daily for two minutes.

Treatment:

Drug: Toothpaste Tablet

Conventional Toothpaste

Active Comparator group

Description:

Subjects are instructed to use the toothpaste at each brushing. Brushing is recommended twice daily for two minutes.

Treatment:

Drug: Conventional Toothpaste