Effectiveness of Ultrapulse for the Treatment of Androgenic Alopecia Among Malaysian: A Quasi-experimental Study

Tunku Abdul Rahman University (UTAR)

Status: Invitation-only

Conditions: Alopecia; Androgenic Alopecia

Treatments: Device: Er:YAG laser

Study type: Interventional

Funder types: Other

Identifiers

NCT06292533

UTAR-30-2024

Details and patient eligibility

About

The goal of this study is to to evaluate the effectiveness of Ultrapulse for the treatment of androgenic alopecia among Malaysian. The main questions it aims to answer are:

• the efficacy of Ultrapulse in treatment of androgenic alopecia among Malaysian
• the safety and adverse effect of Ultrapulse treatment.
• the quality of life of androgenic alopecia among Malaysian.

Full description

Ultrapulse is a is a laser beauty device using erbium-doped yttrium aluminium garnet laser (er:YAG). Er:YAG laser is a laser with wavelength of 2940nm which is able to penetrate into the dermis to a depth of 3-4 mm, and energy absorption occurs in the area of the dermal papilla, resulting in an increase in blood circulation of the papilla and activation of metabolism in the hair follicle. It generates multiple micro pores at the epidermal layer that enhances the absorption of the active substances that help to stimulate hair growth developed by Lyzer Co. Ltd in Korea.

Enrollment: 92 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient with androgenic alopecia with severity of Norwood-Hamilton Scale II to VI for male and Ludwig Scale I to III for female

Exclusion criteria

• Use of topical or systemic medications affecting hair growth within the 6 months before recruitment
• Previous hair transplantation, underwent scalp reconstruction procedure, hair braiding or scalp tattoo

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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92 participants in 2 patient groups

Intervention Group

Experimental group

Description:

Ultrapulse treatment will be delivered by trained beautician for 6 sessions with 2 weeks interval. After the last session, participants will then follow up every 2 weeks for 1 month.

Treatment:

Device: Er:YAG laser

Control-waitlist Group

No Intervention group

Description:

Participants in control-waitlist group will receive homecare treatment that does not interfere with hair growth for 6 sessions with 2 weeks interval, follow up every 2 weeks for 1 month after last session and receive Ultrapulse treatment after the research end.