Effectiveness of Using an Oil Bath Additive

Charité University Medicine Berlin

Status

Completed

Conditions

Xerosis Cutis

Treatments

Other: Balneum oil bath

Study type

Interventional

Funder types

Other

Identifiers

NCT02557698

CRC-SP-ABC-13

Details and patient eligibility

About

Epidermis that lacks moisture and/or sebum presents as dry skin, which is often characterized by a pattern of fine lines, scaling and itching. In dry skin, the barrier function may be compromised. Skin care practices to decrease the risk of development of dry skin and/or to improve dry skin condition have barely been investigated. Bathing with bath oils has been shown to increase skin hydration, thus helping to stabilize skin barrier function. Therefore, the aim of this study is to investigate the effect of bathing every other day on the skin barrier. Functional parameters, such as TEWL, stratum corneum hydration (SCH) and skin-pH (pH) were measured to characterize skin barrier function.

Enrollment

60 patients

Sex

All

Ages

6 months to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Signed informed consent, or children whose parent(s) or guardian(s) have given their written informed consent for their child's participation in the study
Child specific written informed consent, if over 7 years of age
Subjects with a general good and stable health condition
Subjects with clinically stable medical conditions
Accept to abstain from sunbathing and solarium during the study
Overall Dry Skin score (ODS) of 1 to 2 at arms and lower legs
TEWL > 12 g/m2/h on the left mid volar forearm

Exclusion criteria

Any dermatological condition or skin affection which may interfere with the study assessments, e.g. scars
Suffering from porphyria
Suffering from severe photodermatoses according to the judgment of the investigator
Clinically significant, possibly unstable medical conditions such as metastatic tumor
Currently having other malignant or benign tumors of the skin in the investigational area
Any other acute or chronic pathology that may interfere with the study conduct in the investigator's opinion
Known allergy or intolerance to any ingredients of the study product, e.g. propylene glycol
Use of (medical) oil-containing bath additives or other oil-containing cleansers
Current topical or systemic treatment affecting the skin, e.g. diuretics
Treatment of dry and/or inflammatory skin conditions with topical corticosteroids during the 4 weeks before inclusion
Systemic immunosuppressive or immunomodulatory therapy
Topical retinoids applied during the 6 weeks before inclusion
Topical application of immunosuppressive treatment during the 6 weeks before inclusion
Therapeutic UV-Radiation during the 6 weeks before inclusion
Increased UV-exposure during the 6 weeks before inclusion