Effectiveness of Visual Storytelling Intervention on Antibiotic Adherence in UTI Patients (ABR UTI)

Xi'an Jiaotong University

Status: Completed

Conditions: Uncomplicated Urinary Tract Infection; Patient With Uncomplicated UTI

Treatments: Behavioral: Visual Storytelling Intervention for Antibiotic Adherence

Study type: Interventional

Funder types: Other

Identifiers

NCT06885658

BZU-FOPDPP-2466

Details and patient eligibility

About

This study aims to evaluate the effectiveness of a visual storytelling intervention in improving antibiotic adherence among adults with urinary tract infections (UTIs). Participants will be randomly assigned to either the intervention group, where they will receive a visual sticker on their antibiotic packaing, explaining the importance of completing their antibiotic course, or the control group, which will receive routine care. The study will measure how well participants follow their prescribed antibiotic regimens and assess their knowledge and attitudes toward antibiotic use. The goal is to determine if visual storytelling can enhance adherence, reduce antibiotic resistance, and improve health outcomes.

Full description

This randomized controlled trial (RCT) will assess the impact of a visual storytelling intervention on antibiotic adherence among adults diagnosed with uncomplicated urinary tract infections (UTIs). The intervention involves a visually engaging sticker that educates patients on the importance of completing their prescribed antibiotic course and the consequences of non-adherence, such as antibiotic resistance. Participants will be randomly assigned to either the intervention or control group, with the control group receiving standard care (e.g., verbal or written instructions). The primary outcome is adherence to the antibiotic regimen, measured by pill counts. Secondary outcomes include UTI recurrence, knowledge about antibiotic use, and attitudes toward antibiotic treatment. Data will be collected at baseline, immediately after the intervention, and at follow-up visits over 1, 3, and 6 months. This study seeks to determine if visual storytelling can improve antibiotic adherence and help combat antibiotic resistance.

Enrollment: 358 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Adults aged 18 years or older.
2. Physician-confirmed diagnosis of uncomplicated urinary tract infection (UTI).
3. Prescribed oral antibiotics (tablet/capsule) for UTI treatment.
4. Willingness to participate in the study and provide informed consent.
5. Ability to complete follow-up assessments and adhere to the study protocol.

Exclusion criteria

1. Diagnosed with complicated UTI (e.g., pyelonephritis, sepsis, or structural abnormalities).
2. Multiple comorbidities that require polypharmacy.
3. Cognitive impairment or mental disorders that would interfere with study participation.
4. Pregnant or breastfeeding women.
5. Participation in another clinical trial that could interfere with this study.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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358 participants in 2 patient groups

Intervention Arm: Visual Storytelling using stickers

Experimental group

Description:

In this arm, participants will receive a visual storytelling intervention designed to improve antibiotic adherence. The intervention involves a stickers (affixed to the antibiotic packages) containing simple, visually appealing illustrations that explain how antibiotics work and the consequences of not completing the full course. The story contrasts the positive outcomes of adhering to the treatment with the risks of non-adherence, including the development of antibiotic resistance. Key messages will highlight the importance of completing the prescribed antibiotic course. The intervention is intended to engage patients emotionally and cognitively, enhancing their understanding of antibiotic use and encouraging adherence to the prescribed treatment regimen.

Treatment:

Behavioral: Visual Storytelling Intervention for Antibiotic Adherence

Control Group: Standard Care for Antibiotic Adherence

No Intervention group

Description:

The control group will receive the usual standard care for antibiotic adherence, which typically includes verbal or written instructions provided by the healthcare provider about the correct usage of prescribed antibiotics for treating urinary tract infections (UTI). This group will not receive any additional interventions, such as the visual storytelling intervention. The standard care aims to represent the typical approach to UTI treatment, allowing for a comparison of the effectiveness of the visual storytelling intervention against routine practice in improving antibiotic adherence. Participants in this group will also complete the same baseline and follow-up assessments related to knowledge and attitudes about antibiotics and adherence.