Effectivness of Conservative Techniques in Management of PAS

Assiut University

Status: Unknown

Conditions: Placenta Accreta

Treatments: Procedure: conservative tecchniques in management of PAS

Study type: Observational

Funder types: Other

Identifiers

NCT05104177

conservative techniques in PAS

Details and patient eligibility

About

To evaluate the effectiveness of conservative techniques for placenta accreta spectrum to reduce maternal mortality and morbidity

Full description

Placenta accreta spectrum (PAS) represents the spectrum of clinical conditions when part or whole of the placenta becomes abnormally adherent or invades the myometrium . Over the last 40 years, caesarean delivery rates around the world have risen from less than 10% to over 30%, and almost simultaneously a 10-fold increase in the incidence of PAS . PAS is one of the most dangerous conditions of the pregnancy as it is significantly associated with maternal morbidity and mortality .

Ultrasound imaging is the most commonly used technique to diagnose PAS disorders prenatally. There is also wide variation globally on the management of PAS disorders, with some centres opting for a radical approach, whereas others have proposed a range of conservative approaches .

The conservative approaches include one-step conservative surgery, leaving the placenta in situ, the Triple-P procedure, and transverse B-Lynch suture . Recently, Women's health hospital has adopted a new approach for conservative management of most cases of PAS, including wedge resection of the myometrium over the adherent part of the placenta, or a staged-approach following delivery of the fetus starting with meticulous dissection of the urinary bladder form the lower uterine segment, then bilateral uterine artery ligation at a level below the apparent placenta-myometrial bulge, followed by removal of the placenta, after which a catheter is inserted in the cervix and the placental pouch is closed .

Enrollment: 80 estimated patients

Sex: Female

Ages: 19 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. • Gestational age starting from 28 weeks onwards.
2. • Women with at least 1 previous hysterotomy (e.g. Caesarean deliveries, myomectomy)
3. • Elective or emergent Caesarean deliveries

Exclusion criteria

• A pre-existing decision of performing intrapartum hysterectomy