Effects and Mechanism of the Fully Immersive Virtual Reality Cognitive Training Based on Leisure Activities

Chang Gung Medical Foundation

Status: Not yet enrolling

Conditions: MCI; SCD

Treatments: Behavioral: VR cognitive training; Behavioral: Traditional cognitive training

Study type: Interventional

Funder types: Other

Identifiers

NCT05682469

202102478B0

Details and patient eligibility

About

The aim of this study is to identify the effects of the immersive leisure-based VR cognitive training, and compare the intervention effects for elderly with MCI and SCD. The investigators anticipate the VR training can facilitate cognitive function, daily function, quality of life. The investigators anticipated the metabolic biomarkers, mechanism, and brain activities will be found. The significance of this study is identifying the effect of immersive leisure-based VR cognitive training, and confirming the metabolic biomarkers and brain activities. It could improve the accuracy of identification, prevent the progression to dementia, and lead the field of technological assistance to new opportunities for training.

Enrollment: 275 estimated patients

Sex: All

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

MCI Inclusion Criteria:

age>=60 able to follow instruction MoCA<26 Scores on cognitive tests for individuals with MCI are 1 to 1.5 standard deviations below the mean for their age and education matched peers on culturally

SCD Inclusion Criteria:

age>=60 ECog-12 score >1 MoCA>=26; does not conform the standards of MCI and dementia

Exclusion criteria

• dizziness or epilepsy history; neurological or other orthopedic diseases with neurological or other orthopedic diseases unstable physical condition of VR cognitive training Recent psychiatric diagnosis, such as depression

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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275 participants in 2 patient groups

VR group

Experimental group

Description:

VR cognitive training receives eight gardening activities. The cognitive elements including attention, working memory, processing speed, and executive function incorporated training.

Treatment:

Behavioral: VR cognitive training

control group

Active Comparator group

Description:

The control group is performing traditional cognitive training program.

Treatment:

Behavioral: Traditional cognitive training