Effects of a 12-week Combined Exercise Program on Ghrelins in Obese Adolescent Girls

Pusan National University Yangsan Hospital

Status

Completed

Conditions

Ghrelin

Treatments

Other: Control

Other: Combined exercise program

Study type

Interventional

Funder types

Other

Identifiers

NCT04447391

04-2015-015

Details and patient eligibility

About

This study aimed to explore the effects of a 12-week combined exercise on ghrelin O acyl transferase, acylated ghrelin and desacylated ghrelin levels in obese girls.

Full description

Little is known about on ghrelin O acyl transferase (GOAT), acylated ghrelin (AG) and desacylated ghrelin (DAG) levels during long-term exercise in adolescent population. Our previous study showed that combined exercise program in overweight children increases DAG with unchanged AG. This study aimed to explore the effects of a 12-week combined exercise on GOAT, AG, and DAG in obese girls.

Enrollment

30 patients

Sex

Female

Ages

16 to 18 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

girls between 16 and 18 years
being classified as being overweight or obese defined with the 85th percentile of body mass index or above based on the 2007 growth chart for Korean children aged 2-18 years.
After consultation with a physician, they were required to be considered physically healthy enough to engage in regular exercise after school.

Exclusion criteria

participation in any weight-management programme in the past 6 months
engagement in other exercise programs except for regular physical education at school
smoking
amenorrhea for consecutive 2 months or more
being treated for hereditary diseases, mental disorder, hypertension, diabetes mellitus, or musculoskeletal impairments
taking any medication or supplements for weight control