Effects of a 5-Week Probiotic Supplementation Intervention on Markers of Delayed Onset Muscle Soreness

University of Minnesota (UMN)

Status

Begins enrollment this month

Conditions

Exercise Induced Muscle Damage

Delayed Onset Muscle Soreness (DOMS)

Treatments

Dietary Supplement: Lactobacillus casei

Other: Placebo Capsule(s)

Study type

Interventional

Funder types

Other

Identifiers

NCT07219498

Probiotic Supplementation

Details and patient eligibility

About

The purpose of this study is to evaluate how probiotic supplementation (PS) influences post-exercise recovery in healthy, physically active young adults. Researchers aim to determine if the Lactobacillus casei probiotic strain reduces symptoms of delayed onset muscle soreness (DOMS) based on perceived muscle soreness, pressure pain threshold, and power output following exercise induced muscle damage (EIMD).

Enrollment

24 estimated patients

Sex

All

Ages

18 to 30 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

complete a minimum of 150 minutes a week of at least moderate intensity exercise in either an endurance-based or resistance-based training style based on a self-reported physical activity over the past month
good general health with no injuries or health conditions that would affect physical activity
willing to abstain from consistent NSAID use and other probiotic supplements over the course of this study

Exclusion criteria

known musculoskeletal injuries or physical limitations that could interfere with performing the designated physical activity required
underlying conditions that could place them at an increased risk during exercise such as cardiovascular, respiratory, or metabolic diseases
currently take a probiotic supplement, are prescribed and taking an antibiotic during the intervention, or report using NSAIDs or steroids within the recovery time window
report using an NSAID more than twice a week on a regular basis