Effects of a Diet Based on Inulin-rich Vegetables on Gut Health and Nutritional Behaviour in Healthy Humans

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Status

Completed

Conditions

Healthy

Treatments

Other: Diet based on inulin-rich vegetables

Study type

Interventional

Funder types

Other

Identifiers

NCT03540550

B403201627275

Details and patient eligibility

About

Inulin-type fructans (ITF) are fermentable dietary fibres that can confer beneficial health effects through changes in the gut microbiota. However, their effect on gut sensitivity and nutritional behaviour is a matter of debate.

The investigators evaluated, in healthy individuals, the impact of shifting from their usual food habits towards a diet based on the daily consumption of ITF-rich vegetables on gut microbiota, gastro-intestinal symptoms and food-related behaviour.

Enrollment

26 patients

Sex

All

Ages

18 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

BMI between 20 and 25 kg/m²
Caucasian ethnicity
Hydrogen producers (assessed by hydrogen breath test)

Exclusion criteria

Smokers
Laxative consumption (<4 weeks)
Severe intestinal problems
Psychiatric problems or use of antipsychotic
Consumption of antibiotics, pro/prebiotics, fibre dietary supplement, or any molecules that modifies the intestinal transit (<6 weeks)
Specific dietary practise (vegetarian, vegan,...)
Specific dietary treatment (<6 weeks) (e.g. high protein diet)
Excessive alcohol consumption (>3 glasses/day)
Consumption of the following drugs: proton pump inhibitor, antidiabetic drugs, cholesterol lowering drugs
Inconclusive acceptability test (regarding the protocol of the intervention and the vegetables used in the protocol)