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Effects of a Single Dose of Brazil Nuts on Blood Lipids

S

Skogli Health and Rehabilitation Center

Status

Completed

Conditions

Cholesterol Level, High

Treatments

Other: Brazil nut
Other: Coconut

Study type

Interventional

Funder types

Other

Identifiers

NCT05537324
Skonøtt

Details and patient eligibility

About

Several studies have shown that regular intake of nuts may improve blood lipids. However, few studies have investigated the effects on blood lipids after a single intake of nuts. The present study was conducted in order to evaluate the acute effects of a single intake of Brazil nuts on blood lipids.

The study was a non-blinded randomized controlled study with 52 participants, 26 participants in both the Brazil nut group and in the control group. Blood tests were taken at baseline and 3h, 6h, 24h, 7d and 14d after ingestion of either 50g Brazil nuts or an isocaloric amount of coconut flakes. We then conducted an unpaired t-test in order to compare changes in blood lipids between the two groups. P-values < 0.05 were considered statistically significant

Enrollment

52 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Patients who participated in a rehabilitation program over three weeks at a rehabilitation center. Participants were at the rehabilitation center due to rheumatic diseases or chronic pain conditions / fibromyalgia.

Exclusion criteria

  • Food allergy, lactose intolerance, celiac disease, mild illness for the last 3 weeks (infections or inflammatory conditions), serious illness (eg. heart attack) or undergone surgery during the previous 3 months, intake of Brazil four weeks prior study enrollment, using cholesterol-lowering or blood-thinning drugs, planning to eat more than one meal in other places than the rehabilitation center during the study.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

52 participants in 2 patient groups

Brazil nut
Experimental group
Description:
50g Brazil nuts
Treatment:
Other: Brazil nut
Coconut
Other group
Description:
46g Coconut flakes
Treatment:
Other: Coconut

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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