Effects of Activity and Education Program on Patients With Chronic Hepatitis C Infection

National Taiwan University

Status: Unknown

Conditions: Hepatitis C Virus Infection, Response to Therapy of

Treatments: Behavioral: Personalized Physical Activity and Psycho-Education (PPAPE) Program

Study type: Interventional

Funder types: Other

Identifiers

NCT01572233

201103086RC

Details and patient eligibility

About

This 4-year project will be guided by a biobehavioral model for the study of exercise interventions in two phases with the purposes to :

1. explore the patients' physical activity preferences and develop doable activity lists during treatment period
2. examine the changes of health-related physical fitness component over interferon treatment
3. develop the Personalized Physical Activity and Psych-Education (PPAPE) Program and test its effects on decreasing fatigue, physical and psychological distress, and improving their health-related physical fitness and quality of life in patients with chronic hepatitis C receiving Interferon with Ribavirin Combination Therapy
4. evaluate the outcome of the PPAPE program on increasing adherence to therapy, the sustained virological response (SVR) in 24 weeks after the end of treatment, and the time-consuming for education program during intervention.

Enrollment: 300 estimated patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with Chronic Hepatitis C Infection Receiving Interferon Therapy
• Aged above 18

Exclusion criteria

• None

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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300 participants in 2 patient groups

Patient with HCV Infection

Experimental group

Description:

Personalized Physical Activity and Psycho-Education (PPAPE) Program will be tested on this group.

Treatment:

Behavioral: Personalized Physical Activity and Psycho-Education (PPAPE) Program

usual care

No Intervention group

Description:

waiting list group with usual care