Effects of Acute Sugar Intake on Choroidal Thickness

Southern College of Optometry

Status

Enrolling

Conditions

Choroid

Treatments

Dietary Supplement: Oral glucose

Study type

Interventional

Funder types

Other

Identifiers

NCT07376005

2025-12-01PS

Details and patient eligibility

About

This study aims to bridge that gap by investigating how acute sugar intake influences choroidal thickness.

Full description

This investigation will be a prospective, repeated-measures study. All subjects will arrive fasted and will be asked not to consume any outside food or beverages during the three-hour study period, and will be asked to abstain from caffeine intake for 12 hours before participation. A baseline OCT scan of the macula of the right eye will be performed using the Heidelberg Spectralis OCT system. Participants will then consume 30 grams of sugar in the form of glucose tablets. Macular OCT scans of the right eye will be repeated every 30 minutes for 3 hours following sugar consumption.

Enrollment

47 estimated patients

Sex

All

Ages

21 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

In order to be eligible for enrolment, each subject must have less than 6 diopters of spherical equivalent refractive error, and have no existing diagnosis of diabetes or pre-diabetes.

Exclusion criteria

Any potential subject with known retinal pathology will be excluded. Any potential subject with any other known systemic or ocular conditions that may impact their ability to participate in the study or provide generalizable data will also be excluded.