Effects of Aerobic Versus Resistance Training in Post Percutaneous Coronary Intervention Obese Patients

Riphah International University

Status: Completed

Conditions: Cardiovascular Diseases

Treatments: Other: Aerobic Training; Other: Resistance Training

Study type: Interventional

Funder types: Other

Identifiers

NCT06308276

REC/RCR&AHS/23/0363

Details and patient eligibility

About

The randomized clinical trial (RCT) endeavors to enroll 50 participants, divided equally into aerobic exercise and resistance exercise groups. The study employs rigorous tools such as blood pressure measurement, SF-36 questionnaire, and the Six-Minute Walk Test (6MWT) to assess VO2max.

Full description

The randomized clinical trial (RCT) endeavors to enroll 50 participants, divided equally into aerobic exercise and resistance exercise groups. The non-probability convenient sampling technique, followed by random allocation using a lottery method, ensures a diverse yet unbiased sample. Will be conducted at the Sialkot Medical and Physiotherapy Centre, the inclusion criteria will focus on post-PCI patients aged 40-60, presenting with a BMI of 30 or higher. The study employs rigorous tools such as blood pressure measurement, SF-36 questionnaire, and the Six-Minute Walk Test (6MWT) to assess VO2max. The aerobic exercise group undergoes sessions three times a week, progressively increasing in duration and intensity, emphasizing activities like brisk walking and cycling. The resistance exercise group follows a similar schedule, engaging in full-body resistance exercises targeting major muscle groups. Both groups undergo assessments using cardiopulmonary exercise testing (CPET) to determine exercise tolerance accurately.

Enrollment: 50 patients

Sex: All

Ages: 40 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age: Participants must be between 40 and 60 years old.
• Gender: Male and female both.
• Cardiovascular Status: Post Percutaneous Coronary Intervention (PCI) patients with a documented history of coronary artery disease
• Participants who are at least three months post PCI to ensure stabilization of their cardiovascular condition.
• Obesity: Participants must have a Body Mass Index (BMI) equal to or greater than 30 kg/m², indicating obesity.
• Health Status: Participants should be in stable health condition to participate in moderate physical activities.
• Willingness to Participate: Participants must provide informed consent and be willing to comply with the study protocol, including attending scheduled exercise sessions and follow-up assessments.
• Participants capable of engaging in either aerobic or resistance training, were assessed by a physical activity readiness questionnaire (PAR-Q).

Exclusion criteria

• Participants with severe physical limitations, disabilities, or musculoskeletal disorders that would prevent them from engaging in aerobic and resistance exercises.
• Individuals with a history of substance abuse or current substance abuse issues that might interfere with their ability to participate or adhere to the study protocol.
• Patients with Neurological diseases
• Patients with severe or unstable heart conditions, recent heart attack, or heart failure

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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50 participants in 2 patient groups

Group A

Active Comparator group

Description:

Brisk walking, jogging, cycling, or low-impact aerobics

Treatment:

Other: Aerobic Training

Group B

Active Comparator group

Description:

Full body resistance exercise targeting major muscle groups, including squats, lunges, chest presses, rows, and core exercises

Treatment:

Other: Resistance Training