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Effects of Alcohol History on Effects of Sevoflurane and Nitrous Oxide - 13

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The University of Chicago

Status and phase

Completed
Phase 2

Conditions

Opioid-Related Disorders
Substance-Related Disorders
Alcohol-Related Disorders

Treatments

Drug: 0.4% sevoflurane
Other: Placebo
Drug: 30% Nitrous oxide
Drug: 0.2% sevoflurane
Drug: 0.6% sevoflurane

Study type

Interventional

Funder types

Other
NIH

Identifiers

NCT00000261
R01-08391-13
R01DA008391 (U.S. NIH Grant/Contract)
NIDA-08391-13

Details and patient eligibility

About

The purpose of this study is to evaluate the effects of alcohol history on the subjective and reinforcing effects of sevoflurane and nitrous oxide in healthy volunteers. All subjects underwent psychomotor testing during 4 sessions of placebo, drug/placebo, and choice of intervention.

Enrollment

14 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Please contact site for information.

Trial design

14 participants in 1 patient group

Moderate drinking adults
Experimental group
Treatment:
Drug: 0.6% sevoflurane
Drug: 0.2% sevoflurane
Drug: 30% Nitrous oxide
Drug: 0.4% sevoflurane
Other: Placebo

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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