Effects of Alcohol on Simulated Driving

Utrecht Institute for Pharmaceutical Sciences

Status

Completed

Conditions

Alcoholism

Treatments

Drug: alcohol

Study type

Interventional

Funder types

Other

Identifiers

NCT00477984

06-221/O

Details and patient eligibility

About

Previous studies have shown that alcohol significantly impairs driving performance. Acute alcohol administration also has a detrimental effect on secondary task performance during dual-tasks. The present study will investigate the effects of five different dosages of ethanol (0,0.2, 0,5, 0,8 and 1,0 % BAC) on performance in a driving simulator. Steering performance and brain activity will be recorded in both single- and dual-task conditions.

Enrollment

32 patients

Sex

All

Ages

21 to 50 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

He/she is aged between 21-50
Written informed consent
Right-handed
Normal static binocular acuity, corrected or uncorrected
Normal hearing
Social Drinker (average of 7 to 21 alcoholic drinks per week)
Possession of a drivers license
Be considered as reliable and mentally capable of adhering to the protocol.

Exclusion criteria

Current drug use (positive urine drug screen on the presence of amphetamines (including MDMA), barbiturates, cannabinoids, benzodiazepines, cocaine, and opiates)
Positive urine pregnancy drug screen in women
Use of psychoactive medication
Positive alcohol breath test
Prior enrolment in the same study
Physical or mental illness
Excessive alcohol use (>21 alcoholic drinks per week)
Excessive smoking (more than 10 cigarettes per day)
Intake of caffeine-containing beverages over 5 glasses per day