Effects of Allium Hookeri on Blood Glucose

Chonbuk National University

Status: Completed

Conditions: PreDiabetes

Treatments: Dietary Supplement: Allium hookeri extract; Dietary Supplement: Placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT03330366

CTCF2_2015_AH

Details and patient eligibility

About

The researchers investigated the anti-diabetic effects of Allium hookeri root extract for Korean prediabetic participants.

Full description

Allium hookeri root is widely consumed as a vegetable and herbal medicine in Asia. Although the antidiabetic activities of Allium hookeri have been documented in animal studies, the improved effects of Allium hookeri on human are not clear. Therefore, in this study, the researchers investigated whether Allium hookeri root extract could be effective in reducing the risk of type 2 diabetes in individuals with prediabetes.

Enrollment: 30 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Fasting glucose 100~126 mg/dl

Exclusion criteria

• Significant variation in weight (more 10%) in the past 3 months
• Treatment by hypoglycemic and hypolipidemic drug therapy within the past three months
• Type 1 diabetes or HbA1c>9.0%
• Cardiovascular disease
• Hypoglycemic agent, obesity medicine, and lipid lowering agent within past 6 months or blood sugar, obesity, and lipid improvement functional foods within past 2 monts
• Pregnancy or breast feeding

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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30 participants in 2 patient groups, including a placebo group

Allium hookeri extract

Experimental group

Description:

take two capsules per day (486 mg/day) for 8 weeks

Treatment:

Dietary Supplement: Allium hookeri extract

Placebo

Placebo Comparator group

Description:

take two capsules per day for 8 weeks

Treatment:

Dietary Supplement: Placebo