Effects of an Oral Herbal Supplement on Skin Aging, Hydration, and Elasticity

Integrative Skin Science and Research

Status: Not yet enrolling

Conditions: Photoaging

Treatments: Dietary Supplement: Oral herbal supplement; Dietary Supplement: Oral placebo supplement

Study type: Interventional

Funder types: Industry; Other

Identifiers

NCT06146140

i23-09-Vidya_Skin_Supp

Details and patient eligibility

About

The purpose of this study is to evaluate how an oral herbal supplementation influences facial skin elasticity and facial hydration as well as markers of photoaging (erythema and pigmentation).

Full description

Skin is the largest organ of the body and skin aging represents a primary indicator of the aging process in the body. Photoaging is among the most crucial factors that cause skin aging damage. Photoaged skin is primarily induced by prolonged exposure to ultraviolet radiation leading to the appearance of increased skin pigmentation, reduced elasticity, and pronounced wrinkles. There has been an increasing recognition of the influence of nutrition on skin health with dietary elements emerging as a viable alternative approach to preventing photoaging. The aim of this study is to understand how oral supplementation impacts photoaged skin, facial hydration, and facial elasticity.

Enrollment: 36 estimated patients

Sex: Female

Ages: 35 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women who are 35 to 55 years of age

Exclusion criteria

• Individuals who are pregnant or breastfeeding.
• Prisoners.
• Adults unable to consent.
• Those who are unwilling to discontinue topical probiotics, topical hydroquinone, retinoids, bakuchiol, vitamin C, or acetyl zingerone containing products for two weeks to meet the washout criteria prior to enrolling.
• Subjects with any of the following facial cosmetic treatments in the past 3 months or those who are unwilling to withhold the following facial cosmetic treatments during the study including botulinum toxin, injectable fillers, microdermabrasion, intense pulsed light (IPL), peels, laser treatments, acid treatments, facial plastic surgery, or any other medical treatment administered by a physician or skin care professional which is designed to improve the appearance of facial skin.
• Individuals who have changed any of their hormonal based contraception within 3 months prior to joining the study.
• Current tobacco smoker or a tobacco smoking history of greater than 10 pack-years.
• Any known allergy to any of the ingredients in the study product.
• Those who have been on an oral antibiotic within 1 month prior enrolling
• Those who are unwilling to discontinue oral probiotics-based supplementation or supplement ingredients found in the study's oral, product 1 month prior to enrollment

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

---

36 participants in 2 patient groups, including a placebo group

Oral Herbal Supplement

Experimental group

Description:

Oral supplement containing an herbal blend

Treatment:

Dietary Supplement: Oral herbal supplement

Oral Placebo Supplement

Placebo Comparator group

Description:

Oral placebo supplement

Treatment:

Dietary Supplement: Oral placebo supplement