Effects of AN69 ST Hemofilter on Coagulation During Continuous Renal Replacement Therapy in Critically Ill

Southeast University

Status: Unknown

Conditions: Critically Ill; Acute Kidney Injury; Septic Shock

Treatments: Device: AN 69 hemofilter; Device: AN 69 ST hemofilter

Study type: Interventional

Funder types: Other

Identifiers

NCT01823484

112233

Details and patient eligibility

About

Compared with AN69 hemofilter, AN69 ST hemofilter may prolong the time of hemofilter and decrease the quantity of heparin during continuous renal replacement therapy in critically ill.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age> 18 years old
• admitted to ICU and need CRRT
• anticipated survival time >72h

Exclusion criteria

• allergy to hemofilter or heparin
• heparin associated thrombocytopenia
• pregnancy or lactation
• using other anticoagulate drugs

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

40 participants in 2 patient groups

AN 69 ST hemofilter

Experimental group

Description:

Use AN 69 ST hemofilter during CRRT

Treatment:

Device: AN 69 ST hemofilter

AN 69 hemofilter

Active Comparator group

Description:

Use AN 69 hemofilter during CRRT

Treatment:

Device: AN 69 hemofilter