Effects of Antimicrobial Photodynamic Therapy on Regeneration of Class II Furcation Lesions

University of Sao Paulo

Status: Completed

Conditions: Periodontal Diseases; Periodontitis, Chronic; Periodontal Bone Loss

Treatments: Procedure: Scaling and root planing; Drug: Toluidine Blue O

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT03264118

BauruSchoolDentistryfurcation

Details and patient eligibility

About

The aim of this study is to evaluate the additional effect of antimicrobial photodynamic therapy regeneration treatment of mandibular furcation lesions when associated to bovine bone and porcine collagen membrane.

Enrollment: 25 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of class II furcation lesion in mandibular 1st and 2nd molars
• Mandibular 1st and 2nd molars without caries, erosion or abrasion

Exclusion criteria

• Smoking habit
• Pregnancy
• Use of antibiotics in the last six months
• Periodontal treatment in the last six months
• Endodontic lesion
• Systemic diseases that impair wound healing

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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25 participants in 2 patient groups

Control

Active Comparator group

Description:

Decontamination of furcation defect with scaling and root planing only.

Treatment:

Procedure: Scaling and root planing

Antimicrobial Photodynamic Therapy

Experimental group

Description:

Decontamination of furcation defect with scaling and root planing complemented by antimicrobial photodynamic therapy.

Treatment:

Procedure: Scaling and root planing

Drug: Toluidine Blue O